Experts at Costa Rican Vacations Offer Quick Tips for Getting the Most Out of a Vacation to Costa Rica in 2017

NEW YORK, NY, USA, December 30, 2016 /EINPresswire.com/ — San Jose, Costa Rica (December 27, 2016) – Costa Rican Vacations (CRV), a travel agency specializing in personalized, boutique vacations to Costa Rica since 1999, polled its expert vacation planners to create a list of helpful tips for travel to Costa Rica in the New Year!

#1 — Capital city flights can be an advantage. Flights to San Jose can often be cheaper than Liberia — the popular Guanacaste beach locale. Costa Rica’s capital is the most connected locale in the country, making it easy to connect via domestic flights to all major destinations. San Jose is also a great jumping off point for the most visited site in the country – the Arenal Volcano. Most importantly if you do see a well-priced airfare – jump on it right away as they don’t usually last long.

#2 — Go off the beaten path. Costa Rica is one of the safest destinations in Central America. Veer off touristy locales. Authenticity abounds in places like Drake Bay, Orosi Valley and Tortuguero.

#3 — Dust Off your Spanish. Interact with locals! Costa Ricans, affectionately known as “Ticos,” are the warmest, friendliest people on earth! CNN.com labeled this humble country the “happiest place on earth” for a reason. Learn a few words in Spanish and you just may forge valuable relationships.

#4 — Visit no less than two locations. Costa Rica has much to offer – beach, volcanoes, wildlife and more. Don’t limit your first-time visit to just one region! It is easy to fit in two different, but equally exciting destinations while on a trip to Costa Rica!

#5 — Rely on local travel experts! Reading through too much content online can be overwhelming and frustrating. Costa Rican Vacation travel experts live locally and visit properties every week. They make it their mission to know everything about the country and can best pick the resorts and experiences that will suit each individual traveler needs.

#6 — Sample the local food! Costa Rican cuisine is a wonderful way to connect with locals and get a true “flavor” for the culture! Pura Vida Mae — try the gallo pinto!

#7 — Talk to your hotel staff and drivers! This is the best way to get insider information that you won’t find in a book or online. Some of the best experiences are found through the locals that live in the area.

#8 — Bring the family! Costa Rica is super family-friendly and there are activities for children of all ages.

A travel guide with even more great tips for vacations to Costa Rica, can be found online at http://www.vacationscostarica.com/travel-guide/travel-tips/

About Costa Rican Vacations

Costa Rican Vacations (CRV) is a travel company specializing in personalized, boutique vacations to Costa Rica. CRV's staff of globetrotters come from all corners of the world, and have explored every nook and cranny of Costa Rica. They know every destination inside and out, and what is more, they personally vet every experience and only recommend the ones they know will create the best travel experiences. Costa Rican Vacations marries a passion for travel and local expertise, using expert knowledge and insider information to curate true travel experiences. For more information go to www.vacationscostarica.com/ or call 1-800-606-1860

Tory Lorance Weiss
JFC PR
503-803-0714
email us here


Source: EIN Presswire

BET The NEW EDITION Story Jan 24th 9PM ET

BET’S EPIC THREE-NIGHT MINISERIES EVENT “THE NEW EDITION STORY” PREMIERES JANUARY 24 AT 9 PM ET/PT ON BET

NEW YORK, NY, USA, December 30, 2016 /EINPresswire.com/ — New Edition laid the foundation for how modern-day boy bands look, feel, and sound. Boyz II Men, N’SYNC, The Backstreet Boys, and New Kids On The Block all took their cues from Ronnie DeVoe, Ralph Tresvant, Michael Bivins, Bobby Brown, Ricky Bell & Johnny Gill. After 30 years of breaking hearts on the record and from the stage, New Edition finally gets the biopic that their stellar tenure in entertainment so richly deserves. This epic three-part miniseries follows the group from their humble beginnings as kids in Boston to global mega-stardom – weathering the highs and lows of controversy, personnel changes, and the ultimate cost of fame.

The star-filled THE NEW EDITION STORY cast INCLUDES Bryshere Y. Gray Elijah Kelley, Luke James, Keith Powers, Algee Smith, Woody McClain, Dante Hoagland, Caleb McLaughlin, Jahi Winston, Myles Truitt and Tyler Williams as NEW EDITION along with La La Anthony, Yvette Nicole Brown, Monica Calhoun, Lisa Nicole Carson, Sandi McCree Wood Harris, Michael Rapaport, Faizon Love, Duane Martin Tank and Bre-Z.Along with a stellar cast, THE NEW EDITION STORY includes a collective of award-winning producers and directors including iconic music powerhouses James “Jimmy Jam” Harris, Terry Lewis and Kenny “Babyface” Edmonds, Executive Producer Jesse Collins and award-winning director Chris Robinson. THE NEW EDITION STORY will air as a six hour, three night event on January 24, 25, and 26, 2017 at 9 PM ET/PT on BET.

Three Part Breakdown of THE NEW EDITION STORY Miniseries: Part One (2 hours) premieres Tuesday, January 24th at 9 PM /ET/PT

The year is 1978. The city, Roxbury, MA, just outside of Boston. Eleven year old Bobby Brown convinces some friends (Ricky Bell, Mike Bivins, and Ralph Tresvant) to perform in local talent shows in an attempt to win money (and girls). Once the group is formed, they convince a hot local manager, Brooke Payne, to turn them into talent show winners. The boys are eventually discovered by music impresario, Maurice Starr, who signs them to a record deal. They add a fifth member, Ronnie DeVoe, and their debut song “Candy Girl” hits #1 on the charts. Gary Evans, a manager from NYC, promises them a better deal, bigger stardom, and more money. When the boys get a new deal with MCA Records in L.A., things get off to an inauspicious start when MCA president Jheryl Busby, underwhelmed by his new signing, pushes them to deliver a hit album or else.

Part Two (2 hours) premieres Wednesday, January 25th at 9 PM /ET/PT

It’s 1984, and New Edition is in L.A. recording their second album. Ralph, fully aware of the resentment from his bandmates, requests more parts for them to sing. The album is a huge hit; but Bobby’s behavior gets more erratic and outlandish while on the road. Eventually tensions erupt, and the group dynamic takes a pivotal change – the boys vote to kick Bobby out – and New Edition is never the same. Soon Ralph decides that he wants to go solo, leaving remaining members Ricky, Mike, and Ronnie stunned. Mike, the group’s de facto leader, adds R&B singer Johnny Gill to the group. Everything comes to an ugly head when the group meets to record their next album.

Part Three (2 hours) premieres Thursday, January 26th at 9 PM /ET/PT

New Edition’s “Heartbreak” tour is an incredible success and the group is soaring high. Bobby, who has his own hit album “Don’t Be Cruel”, starts off as their opening act. But he soon eclipses them, becoming one of the biggest stars in R&B music. By 1990, all the members have launched hugely successful solo careers – even though there’s tension bubbling under the surface between them. A few short years later when most of the guys are up to their ears in debt, they agree to do a reunion album and tour with all six members, including Bobby. This should be New Edition’s rebirth, but things immediately get off to a bad start. In the aftermath, all six members go their separate ways, trying to navigate life after N.E., leaving little hope to maintain the brotherhood they once shared.

THE NEW EDITION STORY is executive produced by Jesse Collins (Real Husbands of Hollywood) for JCE Films, a division of Jesse Collins Entertainment; directed by Chris Robinson (ATL) and co-produced by Brooke Payne, Ricky Bell, Michael Bivins, Ronnie DeVoe, Johnny Gill, Ralph Tresvant and Bobby Brown.

For behind the scenes look at the making of the film, plus exclusive clips and photos from THE NEW EDITION STORY, log on to http://www.BET.com/shows/the-new-edition-story.html and join the conversation on social media using the hashtag #NewEditionBET.

Gerald
PR MobileWire
305-490-2182
email us here


Source: EIN Presswire

NJ MED joins Global Human Rights Fight

NJ MED plans to be a major force in international programming and services in 2017

“Our purpose is to be aggressive in solving world problems, as it relates to children’s rights. We believe in investing in education, we can help safeguard our future, to assure everyone has a chance

— Albert Mitchell II, Founder and CEO of NJ MED

NEW YORK, NEW YORK, USA, December 30, 2016 /EINPresswire.com/ — NJ MED (New Jersey Minority Educational Development), a nonprofit organization was formed 1995 in the United States. The organization’s mission is to address and resolve the systemic problems of unserved populations by providing innovative programming and technical assistance to existing educational, business, and community organizations.

Mr. Albert Mitchell II, Founder and CEO of NJ MED, stated during their annual report meeting, “Our purpose is to be aggressive in solving world problems, as it relates to children’s rights. We believe in investing in education, we can help safeguard our future, to assure everyone has a chance to reach his or her full potential in life, both economically and socially. “

Mr. Mitchell II also added, “We don’t care to associate with non-doers. We are a can do bunch. As one of our board members pointed out, we are like a combat medic; we are on the human rights frontline battlefield, providing aide to the people that are or have been wounded. This is not a job or game, this is our reality.”

NJ MED international presents has grown, by becoming a consultative member of the United Nation’s, largest subsidiary body, Economic and Social Council (ECOSOC), in 2016.

Mr. Mitchell II said, “With this status, we now have the capability to build international relationships with other NGOs, to reach all 198 countries that are a member of the UN.”

NJ MED’s current programs and services include:
• The 100% Graduation Rate Program- that works with at-risk minority males, towards social skill development and economic training
• US Student Pledge Campaign – that helps prepare a higher-skilled US future workforce
• Graduation Week Campaign – that promotes local high school graduation classes across the US
• The World Top 20 Poll – that ranks and monitors the educational development of students from 3 to 25 year olds from 209 nations
• World Top 20 Project – that works with other NGOs to assure every child on the planet has access to education, in a safe and nurturing environment
• Global Universities Rankings – that measures the quality of education and training for students 18 to 25 year olds, as well as, the university’s economic and social impact in promoting their country’s sustainable development
Global Education Report – an annual international survey of students, parents, teachers, educators and tax-payers, to identify areas of needs to improve the quality of education in their country

For more information about NJ MED, and their upcoming activities in 2017, you can schedule an interview at support@worldtop20.org . Please, use Request for Interview as the subject title, and provide your name, organization, with a request date for the interview.

Shomari Moore
NJMED
N/A
email us here


Source: EIN Presswire

The First-Ever Educator-Chosen STEM List is Announced

Four national teachers’ groups and the CBC have chosen the 31 best STEM books

NEW YORK, NY, UNITED STATES, December 29, 2016 /EINPresswire.com/ — The Children’s Book Council (CBC) has announced the Best STEM Books list, the first-ever teacher-approved STEM list for educators, librarians, parents, and guardians for exceptional books with STEM content. Four groups reviewed and determined the 31 Best STEM titles, culled from a list of 328 submissions: the American Society for Engineering Education (ASEE), the International Technology and Engineering Educators Association (ITEEA), the National Science Teachers Association (NSTA), and the Society of Elementary Presidential Awardees (SEPA).

The 2017 Preview List is now available at www.cbcbooks.org/best-stem/, with a fully annotated list to follow in January 2017.

The project was coordinated by the Children’s Book Council over a four-month nomination and voting period.

About the Children’s Book Council (CBC): The Children’s Book Council is the nonprofit trade association for children’s book publishers in North America. The CBC also runs one of the country’s most prestigious literacy charities, Every Child a Reader.

Emma Kantor
The Children's Book Council and Every Child a Reader
2016744136
email us here


Source: EIN Presswire

Maestro Program Graduates Two Top Realtors

Julian Armas/Branch Manager

Donnamarie Chaimanis/Regional VP Luxury Divison

Laffey Real Estate Embraces Program Focused on Leadership Mastery

By creating a leadership platform for managers, LeadingRE has raised the bar for its member brokerages. The program has a highly effective curriculum that can be applied to produce tangible results.

— Julian Armas/Branch Manager

GREENVALE, NEW YORK, UNITED STATES, December 27, 2016 /EINPresswire.com/ — Laffey Real Estate recognizes Julian Armas and Donnamarie Chaimanis as 2016 graduates of prestigious MAESTRO Leadership Certification Program.

Leading Real Estate Companies of the World (LeadingRE) launched the pilot one year ago in the style of an executive MBA course. The six-month leadership training course is for real estate managers to develop talented and highly effective real estate leaders within their own markets. LeadingRE created MAESTRO to develop and enhance the leadership and coaching skills of managers within LeadingRE brokerages to further equip them to take their agents and offices to even higher performance levels with increased confidence and proven methodology.

Julian Armas and Donnamarie Chaimanis, along with 30 other real estate sales managers from top brokerages around the country, graduated from the critically acclaimed program. Based on proprietary and validated research conducted by LeadingRE with 300 sales managers, the rigorous MAESTRO program encompasses three pillars of great office leadership, as determined by the research. It is the first program of its kind in the industry, with the goal of using science and art to establish and practice leadership mastery.
Open only to members of LeadingRE, the program has been designed by a lead faculty comprised of Mike Staver of The Staver Group and practicing real estate leaders Rosey Koberlein, CEO of Long Realty, and Phyllis Brookshire, president of Allen Tate Realtors, along with a number of other subject matter experts from within the industry and beyond it.

Participants, who applied to be accepted into the program, attended three live sessions held at LeadingRE’s Chicago headquarters that included lectures and interactive workshops incorporating ‘real life’ exercises, case studies and group activities. Ongoing support from staff and fellow participants ensures continued engagement and measurable results from the program.

Julian Armas, Branch Manager, has a history of embracing professional enrichment. A two time Floyd Wickman Team Leader, Julian’s fifteen years in real estate have shown him that in order to stay relevant you have to continue to learn. “By creating a leadership platform for branch and sales managers, LeadingRE has raised the bar for its member brokerages,” offered Armas when asked about the merits of the program. The Maestro program is one-of-a-kind, highly effective curriculum that can be applied to produce tangible results.”

Donnamarie Chaimanis, Regional VP Luxury Division, used the opportunity to enhance her leadership skill sets. With just over a decade in residential real estate, Donnamarie recognized how the MAESTRO program could impact the way she conducted business in the future. “Great leaders learn from awesome mentors who have a true commitment to success,” explained Chaimanis. “Maestro raises the bar through enhancements and a sales development program of leaders. Rethinking your audience commands a great Maestro. I am honored to have been selected to join an amazing group of leaders from all over the country.”

“We are delighted to have such an accomplished group of professionals graduate from our MAESTRO Leadership program,” said LeadingRE President/CEO Pam O’Connor. “Their commitment to enhancing their leadership and coaching skills so they can take their agents and offices to even higher performance levels is commendable, and we congratulate them on this achievement.”

Both Armas and Chaimanis were among a prestigious group of participants from 14 states, as well as Mexico. Graduation took place on the past day of the Program with each participant being recognized individually for their commitment and accomplishment of the program. Program graduates will be acknowledged at the upcoming Leading Real Estate Companies of the World® (LeadingRE) Sales Manager SUMMIT taking place March 3-5 at the Fountainebleau Miami Beach, Florida.

About Laffey Real Estate
Laffey Real Estate is one of the largest privately held independent family-owned residential real estate firms on Long Island with a network of over 400 agents in 13 offices throughout Nassau, Western Suffolk and Queens Counties. Their global partnership with Leading Real Estate Companies of the World and Luxury Portfolio, extends their reach to more than 50 countries worldwide. The firm is a full-service provider offering expertise in sales, rentals, relocation, mortgage, developments and title insurance to the marketplace. The cutting-edge technology supporting field agents, premium brand identity and industry-leading tools embody best in class standards. Consumers trust in the Laffey Real Estate name to provide tools and resources that help navigate the process of buying and selling residential real estate in any economic environment. Consistently ranked in the top 10% of the brokers locally and as a Top 500 Broker in the US based on the 2015 Real Trends reports, Laffey Real Estate has an exceptional

Cathy M Poturny/SVP Marketing & Media Relations
Laffey Real Estate
516-626-1500 x390
email us here


Source: EIN Presswire

NATIONAL WOMEN’S MONEY® WEEK ANNOUNCES ILLINOIS PROGRAM AMBASSADOR, SHARON D. MALLORY

Sharon D. Mallory, CEO of SDM Investments, LLC
working with non-profit to create financial resiliency for Illinois women

CHICAGO, ILLINOIS, USA, December 30, 2016 /EINPresswire.com/ — Today, Women's Money® proudly announced that Sharon D. Mallory has been named a National Women’s Money® Week Ambassador for Illinois.

National Women's Money® Week (#WMWeek17) is a national nonprofit campaign that includes live events, online education, and social media events to highlight the resources and need for financial resiliency of women and families. This national program is organized by Women's Money®, a non-profit organization, providing services and resources to women who seek a path toward financial resiliency.

Sharon D. Mallory is the Chief Executive Officer at SDM Investments, LLC a registered investment advisory firm in Merrillville, Indiana and Chicago, Illinois. Sharon began her career in corporate America as a financial advisor in 1992 and launched SDM Investments LLC, in 2006. She has an extensive background in leadership and sales.

Sharon created the NIA Group, a non-profit financial literacy organization, to educate the people in urban communities about personal money management. Sharon has developed curriculum for children and volunteers as a facilitator on budgeting basics to middle school students under the program Mud Pies to Mutual Funds. She recently authored the books Drama, Dollars and Dreams: A Diva’s Guide to Financial Management and 77 Wealth Wisdom Tips. Her articles have appeared in Indiana Minority Business Magazine and The American Association of Individual Investors Magazine. She is also featured in the TD Ameritrade Human Finance Project.

Sharon attended Purdue University in Lafayette, IN where she received her BA degree prior to pursuing advanced degrees at Chicago State University and the University of Colorado’s School of Financial Planning. She received her Chartered Mutual Fund Counselor (CMFC) designation from the University of Colorado. She holds her FINRA series 6, 63, 65 securities licenses, and life and health insurance licenses in various states in which the firm is registered.

"We are very excited to work with Sharon in leading the effort in Illinois," said Women's Money® President and Founder Gina Robison-Billups. "Her expertise and ability to connect with women on a very scary topic makes her a perfect candidate to represent the concerns affecting the financial wellness of Illinois families.”

About Women's Money®

Women's Money®, a 501c3 non-profit organization, completely funded by sponsorships and donations, has developed and delivers a unique and proprietary financial education and accountability system to help women move from financial fragility to financial resiliency.

Women’s Money®, a national organization, successfully piloted its innovative financial education program in Nevada in 2012. The organization produces the Women’s Money® Conferences – one of the top financial education conferences in the nation, and La Conferencia de Mujeres y Dinero® – the only personal financial education conference completely in Spanish in the U.S. The organization also hosts National Women’s Money® Week from January 1-7 – an awareness and education campaign highlighting the importance of financial education for women. Additionally, Women's Money® delivers its proprietary mentoring program to women and girls nationwide. The program has received the National Association of State Treasurer's Pinnacle Award, National Plutus Award Finalist recognition, and has been featured in the New York Times, Woman's World Magazine, USA Today, and Forbes.

# # #

Karen Williams
SDM Investments, LLC
888-988-0858
email us here


Source: EIN Presswire

PBS Newshour Features Gene Luen Yang, Reading Advocate

Reading Without Walls

Major Interview with the National Ambassador for Young People’s Literature

NEW YORK, NY, USA, December 28, 2016 /EINPresswire.com/ — A long-awaited interview with Gene Luen Yang, the National Ambassador for Young People’s Literature, aired on the PBS Newshour right before the holidays on December 22.

You can view the full clip here, in which Gene talks about his vision for Reading Without Walls, a concept he’s developed to encourage children and teens to read a book that’s a window into other lives and cultures, not a mirror of their own. Yang is also an advocate for the enjoyment of graphic novels and the learning of computer coding skills by young people.

Gene Yang is in his second year as the National Ambassador for Young People’s Literature, a program sponsored by the Library of Congress and Every Child a Reader. A national Reading Without Walls Challenge will be offered across America in April 2017.

To learn more about Gene, visit his site http://geneyang.com/

Learn more about the National Ambassador program and the vital role of the Library of Congress. http://www.read.gov/cfb/ambassador/

Every Child a Reader is a literacy organization that runs popular national programs including the Children’s and Teen Choice Book Awards, Children’s Book Week (May 1-7, 2017), and the National Ambassador for Young People’s Literature. Every Child a Reader is a 501(c)(3) charity funded by individual and corporate donations and by the support of The Children’s Book Council.

Carl Lennertz
Trusted Source PR
917-301-7872
email us here


Source: EIN Presswire

Every Child a Reader Launches New Website

Visit the national literacy nonprofit at EveryChildaReader.net

NEW YORK, NY, UNITED STATES, December 28, 2016 /EINPresswire.com/ — Every Child a Reader, the 501(c)(3) nonprofit dedicated to inspiring a love of reading in children and teens across America, has launched a new website for the new year. Every Child a Reader’s popular national programs are now front and center at EveryChildaReader.net. Teachers, librarians, booksellers, and parents will find information on the website for Children’s Book Week, the longest-running literacy initiative in the country; the Children’s and Teen Choice Book Awards, the only book awards chosen by children and teens; and the National Ambassador for Young People’s Literature program, in partnership with the Library of Congress.

A Razoo donation widget is embedded on the Every Child a Reader homepage for a hassle-free donation process, in time for year-end giving. All proceeds go toward the creation of free reading materials for libraries and classrooms.

In the new year, free downloadable resources for Children’s Book Week (May 1-7, 2017), including a digital toolkit, event ideas, and an interactive event map, will be made available starting January 9, 2017 at EveryChildaReader.net/cbw.php. The Every Child a Reader site will also house online voting for the Children’s and Teen Choice Book Awards, open February 28 through May 7, 2017.

Every Child a Reader is a 501(c)(3) nonprofit dedicated to inspiring a love of reading in children and teens across America, and is supported by individual donations, grants, foundations, and the Children’s Book Council.

Emma Kantor
The Children's Book Council and Every Child a Reader
2016744136
email us here


Source: EIN Presswire

LAFFEY REAL ESTATE UNVEILS ASSISTANT MANAGER PROGRAM

Shaheen Abadin/Laffey Real Estate

Allison Platt/Laffey Real Estate

Sandeep Shrivastav/Laffey Real Estate

Brokerage Elevates Corporate Development in 2017

Beginning with our new brand launch and closing out 2016 with the introduction of the AM program, this is the change and forward motion that will keep the firm at forefront of our industry.

— Mark T. Laffey, Principal

GREENVALE, NEW YORK, UNITED STATES, December 27, 2016 /EINPresswire.com/ — Laffey Real Estate, a leader in agent based training and career enhancement, has announced the creation of the firm’s first assistant manager program. Mentored by senior staff, the goal is to transition select Licensed Real Estate Professionals into managerial roles.

The first three participants in the program are Shaheen Abadin, Licensed Real Estate Salesperson/Jackson Heights Office, Allison Platt, Licensed Associate Real Estate Broker/Great Neck Office and Sandeep Shrivistav, Licensed Associate Real Estate Broker/Little Neck Office.

The program focuses on developing sales skills, public speaking, office administration and service efficiency for this new breed of producing Assistant managers. Mentors, in the form of Branch Managers, and mentees are matched based on various factors and will be immersed into their new roles throughout the yearlong program. Mentors and mentees both benefit from the pairing and will be able to share their experiences and knowledge of the organization.

“Jack Welch famously said ‘Change before you have to’ and he was spot on right. This has been a year of immense change for our firm”, explained Mark T. Laffey/Principal Laffey Real Estate. “Beginning with our new brand launch and closing out 2016 with the introduction of the AM program, this is the change and forward motion that will keep the firm at forefront of our industry.”

Shaheen Abadin, Licensed Real Estate Salesperson, began her real estate career twelve years ago. She is with the Jackson Heights Office and will work closely with Manager, Julian Armas, who just completed the Maestro leadership program with Leading Real Estate Companies of the World.

Allison Platt, Licensed Associate Real Estate Broker, a graduate of George Washington University School of Government with a concentration in marketing, has been in residential real estate just over two decades. Her expertise in condo and co-op sales earned her many accolades as well as the respect of her peers and brokers.

Sandeep Shrivastav, Licensed Associate Real Estate Broker, began his career in 2002. He is multi-lingual and utilizes these skills to navigate the multicultural landscape of buyers and sellers across the Queens market.

The program is facilitated through real time activities focused on leadership skills, driving sales and profit, presentation standards and branch operations. Their mentors serve as coach, training coordinator and supervisor, providing ongoing guidance the program.

Ultimately, an Assistant Manager will be able to individualize agent and staff strengths to maximize performance. They will also possess the ability to leverage external data and the firm’s statistical research to provide comprehensive understanding of a diverse and wide ranging customer network. By the nature of the program, this construct will strengthen the collaborative nature of manager and agent with innovative thinking and strategic planning.

An experienced and career motivated Laffey Realtor can work with leads, make appointments with buyer and sellers, generate market analytics, negotiate deals and market within their professional networks. This program is designed to develop future leaders in the firm and not just independently successful real estate agents.

The executive management team welcomes all three of these seasoned professionals and looks forward to working closely together in 2017.

About Laffey Real Estate
Laffey Real Estate is one of the largest privately held independent family-owned residential real estate firms on Long Island with a network of over 400 agents in 13 offices throughout Nassau, Western Suffolk and Queens Counties. Their global partnership with Leading Real Estate Companies of the World and Luxury Portfolio, extends their reach to more than 50 countries worldwide. The firm is a full-service provider offering expertise in sales, rentals, relocation, mortgage, developments and title insurance to the marketplace. The cutting-edge technology supporting field agents, premium brand identity and industry-leading tools embody best in class standards. Consumers trust in the Laffey Real Estate name to provide tools and resources that help navigate the process of buying and selling residential real estate in any economic environment. Consistently ranked in the top 10% of the brokers locally and as a Top 500 Broker in the US based on the 2015 Real Trends reports, Laffey Real Estate has an exceptional

Cathy M Poturny/SVP Marketing & Media Relations
Laffey Real Estate
516-626-1500 x390
email us here


Source: EIN Presswire

How Formaspace Helped Sequence the Human Genome

The Human Genome

DNA sequencing

Steven Riedmuller, who was Senior Director of Field Applications at TIGR at the time

When Craig Venter’s team was sequencing the first human genome, TIGR relied on FORMASPACE to give them a competitive edge over publicly-funded contesting labs.

Time for required for Formaspace to fabricate and deliver? A mere 8 weeks from start to finish.

— Steven Riedmuller

AUSTIN, TEXAS, UNITED STATES, December 6, 2016 /EINPresswire.com/ — Since the Human Genome was decoded in the early 2000s, we take a lot of things for granted that would have been considered science fiction just a few generations earlier. Consider the following:

We now consider it normal to collect DNA samples as evidence at a crime scene to implicate (or exonerate) suspects. Taking this further, residents of upscale New York City co-ops have even gone as far as testing doggie poo to nab the dog owners who don’t clean up after their pets.
We can take a swab sample (often in the comfort of our own home) to determine which viruses we have been exposed to during our lifetime, identify diseases which our individual genes might make us more likely to develop, or get insight into our ancestral genetic racial heritage. We can even get our own dogs tested to determine their breed backgrounds.
Doctors can now provide personalized medicine (pharmacogenomics) at leading healthcare institutions, like MD Anderson Cancer Center, which tests patients for their unique genetic makeup in order to provide ‘precision medicine’ cancer treatments. Eventually, the “Moon Shot”, or the cure-all for cancer, could also be readily available.
Public health officials and investigators can identify strain variations of disease pathogens, ranging from MRSA and HIV to Anthrax, making it possible in many cases to determine the source of a disease outbreak.
How did laboratory scientists break the code of the Human Genome?
Let’s roll the clock back to the immediate post-World War II period. Cambridge University graduate Frederick Sanger began his career studying insulin protein at the National Institute for Medical Research in London. This work led the Nobel Committee to award Sanger a Nobel Prize for successfully sequencing insulin and determining conclusively that amino acid proteins had a defined, regular sequence.

While Sanger had been studying insulin in London, British scientist Francis Crick and American researcher James D. Watson proposed a novel solution to explain the structure of DNA — two strands of DNA coiled together to form a double helix.

Importantly, they theorized that genetic information flowed in one direction — from DNA to RNA, then from RNA to proteins. (Previously many scientists, including Sanger, thought proteins — not DNA — were the source of genetic information.)

An experiment comparing regular hemoglobin with hemoglobin affected by sickle-cell anemia confirmed the new DNA replication hypothesis.

Sanger eventually joined Crick and Watson at Cambridge, where he studied how DNA makes proteins using messenger RNA (mRNA) and transfer RNA (tRNA) at the new Laboratory of Molecular Biology (LMB).

Meanwhile other researchers around the world were making progress. Robert Holley’s team at Cornell was the first the sequence alanine transfer RNA (tRNA) from yeast; it contained 77 nucleotides.

The first DNA sequencing breakthrough came from researchers Wu and Kaiser, who used DNA polymerase to sequence a small fragment of lambda bacteriophage DNA; making it the first time DNA had been sequenced.

The number of identified DNA sequences began to grow and grow.

By 1977, Sanger identified the first complete genome of an organism, the phi X 174 bacteriophage, containing 5,386 nucleotides.

Sanger and Coulson published their gene sequencing technique in 1977 — today known as “Sanger’s Method” — which uses dideoxynucleotides to control the DNA polymerase reactions.

Meanwhile, Allan Maxam and Walter Gilbert had developed their own technique that could sequence double-stranded DNA, making it a superior method despite the use of highly toxic chemicals.

However, in the end, Sanger’s Method became the dominant first-generation sequencing technique when Bruno Gronenborn and Joachim Messing demonstrated they could insert a double-stranded DNA into a single-stranded M13 bacteriophage. This bacteriophage would then ‘clone’ the DNA sequence into single strands of DNA – making it was suitable for analysis using the Sanger’s Method.

For their scientific research, Maxam, Gilbert and Sanger were awarded the 1980 Nobel Prize in Chemistry, making Sanger a rare two-time winner. In 1983 Frederick Sanger retired; he passed away in 2013.

(Bacteriophage viruses are in the news lately. They are the ‘knives’ used to cut DNA in the CRISPR/Cas9 technique we have written about previously.)

The Rise of Automation Techniques for Gene Sequencing
As the scope of DNA sequencing projects grew, it became imperative to develop computer software and laboratory automation systems to process and interpret the vast amount of data. By the late 1970s, researchers like Roger Staden at the LMB were programming minicomputers to manipulate scientific data.

In the late 1980s, the Caltech scientists introduced the AB370, the first automated DNA sequencer. It used fluorescent dyes to identify DNA bases, rather than radioactive tagging used in the classic Sanger’s Method. Soon the new DNA sequencers were fast enough to sequence 50,000 bases in a few hours – previously the same task took a full man-year to complete.

The Start of the Human Genome Project

With the successful completion of a three year project to sequence human mitochondrial DNA, it was time to tackle the biggest objective of all: sequencing the entire human DNA.

The Human Genome Project was launched in 1990 with a budget of $3 billion, with participants from science labs around the world.

But it turns out they were not the only ones wanting a crack at the problem. In 1992, American researcher J. Craig Venter left the National Institutes of Health to establish his own research unit called The Institute for Genomic Research (TIGR).

In 1998, Venter established another new venture called Celera Genomics, whose goal was to sequence the human genome faster than the public-funded Human Genome Project — using a method called whole genome “shotgun” sequencing.

We spoke with Steven Riedmuller, who was Senior Director of Field Applications at TIGR at the time.

During Steven Riedmuller’s tenure as the Laboratory Automation Manager at TIGR, the race between Venter’s team and The Human Genome Project was coming down to the wire. Which team would decode the Human Genome first?

In response to the challenge, Venter’s organization went big: they decided they needed to double their genetic sequencing capacity as soon as physically possible.

But despite the herculean effort, the TIGR facility had a physical capacity problem — one that many laboratory managers face every day. How could they fit double the amount of lab equipment (in this case DNA sequencers) when there simply wasn’t enough space in the existing lab?

The easy answer, facility expansion, was out of the question. There wasn’t time to lease another building, much less equip it. And the cost for that was going to be a budget buster.

That’s when TIGR’s Laboratory Automation Manager, Steven Riedmuller, called Formaspace to see how we could help them out with an innovative solution.

What we discovered is that weight and cost were two important issues. The sequencers at TIGR were heavy (weighing in at 400 pounds each) and valuable — each sequencer unit cost around $140,000 each!

Here at Formaspace, we knew even our standard workbenches were strong enough to ensure that these heavy, expensive sequencers were secure and stable. The trick was to find a way to increase the capacity of the TIGR laboratory without increasing their square footage footprint.

The solution? We fabricated heavy-duty modular workbenches that nested together in a double stack – allowing TIGR to use twice the number of sequencers in their existing laboratory footprint.

The result: TIGR doubled their DNA sequencing productivity rate — and, very importantly — they avoided having to fork over $5 million dollars on a time consuming real-estate expansion.

Time for required for Formaspace to fabricate and deliver? A mere 8 weeks from start to finish.

Read More. https://formaspace.com/articles/laboratory-furniture/formaspace-helped-sequence-human-genome/?utm_source=einpresswire&utm_medium=content&utm_campaign=article-06072016

Mehmet Atesoglu
Formaspace
8002511505
email us here


Source: EIN Presswire